About the Laboratory
Laboratory of Experimental Cardiology was established in 1991. The team comprises 10 members including four doctors of sciences, one professor, and four candidates of sciences. Members of the laboratory defended 4 dissertations for degree of doctor of sciences and 15 dissertations for degree of candidate of sciences. 368 scientific articles indexed by Scopus and three books have been published. 13 patents of inventions of the Russian Federation were received.
Main areas of scientific research
The study of cardioprotective properties of opioids and cannabinoids. The study of receptor and signaling mechanisms of
Data showed that the activation of peripheral opioid receptors increases the resistance of the heart to arrhythmogenic action of
The study showed that the stimulation of peripheral µ2-, δ2-, and κ-opioid receptors as well as the activation of cannabinoid receptors prevent reperfusion injury of the heart i.e. imitate the phenomenon of postconditioning. The signaling mechanism of cardioprotective effects of cannabinoids and opioids was studied. The receptor and signaling nature of the
The studies devoted to cardiovascular effects of cold adaptation have been initiated. Data showed that the activation of β
Members of the laboratory perform the studies aimed at creation of new drugs based on opioids and cannabinoids.
Laboratory of Experimental Cardiology closely collaborates with the researchers from the USA, Great Britain, Czech Republic, Israel, China, Belarus, and Ukraine as seen from joint articles and grants.